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Human TGFb1 Protein, Recombinant


產(chǎn)品貨號(hào):PR00047HuM1
   
詢(xún)價(jià)

規(guī)格    100ug

產(chǎn)品名稱(chēng)Human TGFb1 Protein, Recombinant
 
純度≥95 % as determined by SDS-PAGE
 
內(nèi)毒素< 1.0 EU per μg of the protein as determined by the LAL method
 
生物活性/
 
序列起止Ala279-Ser390
 
標(biāo)簽N-His tag
 
Uniprot鏈接P01137
 
表達(dá)系統(tǒng)293F
 
種屬Human
 
預(yù)測(cè) N 端Met
 
預(yù)測(cè)分子量12.32
 
緩沖液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
運(yùn)輸方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
穩(wěn)定性 & 儲(chǔ)存條件Store for up to one year at -20°C to -80°C as lyophilized powder.
 
復(fù)溶Please refer to COA for detailed information
 
質(zhì)量驗(yàn)證圖:/

別稱(chēng)LAP/TGFB
 
背景信息TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).

全稱(chēng)Transforming growth factor beta-1 proprotein (TGFB1)

說(shuō)明書(shū)待上傳