国人国产免费av影院_日韩精品在线播放日韩中文字幕精品一区在线_豆奶视频成人版在线观看视频_亚洲色图自拍偷拍另类无码_字幕网最新中文资源站_欧美人禽zozk伦交_国产剧情秘 精品三级_A级黄色在线观看_中文字幕在线免费观看网址_久久成人国产夜夜

Human CTSB Protein, Recombinant

產(chǎn)品貨號:PR00450HuP3
   
詢價

規(guī)格:100ug

產(chǎn)品名稱Human CTSB Protein, Recombinant
 
純度≥95 % as determined by SDS-PAGE
 
內(nèi)毒素/
 
生物活性/
 
序列起止Phe74~Ile339
 
標簽C-His tag
 
Uniprot鏈接P07858
 
表達系統(tǒng)E.coli
 
種屬Human
 
預測 N 端Met
 
預測分子量/
 
緩沖液20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
 
運輸方式This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
穩(wěn)定性 & 儲存條件Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
 
復溶Please refer to COA for detailed information
 
別稱CTS-B, APPS, CPSB, APP secretase
 
背景信息Cathepsin B. Cathepsin B is the first described member of the family of lysosomal cysteine proteases (1). Cathepsin B possesses both endopeptidase and exopeptidase activities, in the latter case acting as a peptidyl-dipeptidase. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI) (2 - 4). Therefore, Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Because of its increased levels and redistribution of the enzyme in human and animal tumors, Cathepsin B may also have role in invasion and metastasis (5).In addition to lysosome, Cathepsin B can be secreted or associated with plasma membrane, cytoplasm, and nucleus. It is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme (1).
 
全稱Cathepsin B (CTSB)
 
說明書待上傳