產(chǎn)品名稱：Human MAP3K5 Protein, Recombinant
純度：≥95 % as determined by SDS-PAGE
內(nèi)毒素：< 1.0 EU per μg of the protein as determined by the LAL method
生物活性：/
序列起止：1011~1196
標(biāo)簽：N-His tag
Uniprot鏈接：Q99683
表達(dá)系統(tǒng)：CHOS
種屬：Human
預(yù)測 N 端：Met
預(yù)測分子量：/
緩沖液：20mM Tris, 250mM imidazole, 500mM NaCl, pH8.0, containing 10% glycerol.
運(yùn)輸方式：This Protein is shipped as lyophilized powder at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
穩(wěn)定性 & 儲(chǔ)存條件：Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
復(fù)溶：Please refer to COA for detailed information
質(zhì)量驗(yàn)證圖：/
別稱：MAP3-K5, MAP3K5, ASK1, MAPKKK5, MEKK5, Mitogen-Activated Protein Kinase Kinase Kinase 5, MAPK/ERK kinase kinase 5
背景信息：ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.
全稱：Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)