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Anti-β-Catenin Antibody, Recombinant Antibody

產(chǎn)品編號(hào):RMAP0E7M1
   
詢價(jià)

規(guī)格     100ug

產(chǎn)品名稱Anti-β-Catenin Antibody, Recombinant Antibody
 
經(jīng)驗(yàn)證的應(yīng)用IHC
 
交叉反應(yīng)/
 
特異性/
 
免疫原/
 
制備方法/
 
來源Recombinant Antibody
 
純化Protein A purified
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài)Liquid
 
運(yùn)輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲(chǔ)存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
別稱Beta-catenin
 
背景信息The catenins, (alpha, beta and gamma) are cytoplasmic proteins which bind to the highly conserved tail of the E-cadherin molecule. Beta-catenin is a component of the adherens junction, a multiprotein complex which supports Ca2+ -dependent cell-to-cell contact, which in itself is critical for adhesion, signal transmission and for anchoring the actin cytoskeleton. Beta-catenin's role is as a transcription effector of the wnt-signaling pathway. Immunohistochemistry is the best way to demonstrate nuclear expression of beta-catenin and wnt-pathway activation. This aberrant expression is observed in human tumorigenesis, and especially in colorectal cancer.

全稱/
 
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