Anti-Phospho-MEK1/2 (Ser217/221) Antibody, Recombinant Antibody

產(chǎn)品編號(hào)：RPTMB5A1

￥ 詢價(jià)

規(guī)格 100ug

產(chǎn)品名稱：Anti-Phospho-MEK1/2 (Ser217/221) Antibody, Recombinant Antibody

克隆號(hào)：/

抗體亞型：/

經(jīng)驗(yàn)證的應(yīng)用：WB/IP

交叉反應(yīng)：Human, Mouse, Rat, Monkey

特異性：Recognizes Phospho-MEK1/2 (Ser217/221)

免疫原：Synthetic peptide

制備方法：/

來(lái)源：Recombinant Rabbit IgG

純化：Protein A purified

緩沖液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4

偶聯(lián)物：Unconjugated

狀態(tài)：Liquid

運(yùn)輸方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.

儲(chǔ)存條件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

別稱：/

背景信息：MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation. Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. MEK1/2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx. Constitutively active forms of MEK1/2 are sufficient for the transformation of NIH/3T3 cells or the differentiation of PC-12 cells. MEK activates p44 and p42 MAP kinase by phosphorylating both threonine and tyrosine residues at sites located within the activation loop of kinase subdomain VIII.

全稱：/

說(shuō)明書：待上傳