国人国产免费av影院_日韩精品在线播放日韩中文字幕精品一区在线_豆奶视频成人版在线观看视频_亚洲色图自拍偷拍另类无码_字幕网最新中文资源站_欧美人禽zozk伦交_国产剧情秘 精品三级_A级黄色在线观看_中文字幕在线免费观看网址_久久成人国产夜夜

Anti-ERBB2 Antibody, Rabbit Polyclonal

產(chǎn)品編號:PA00188HuA10
   
詢價

規(guī)格     50uL  100uL  200uL  可選

產(chǎn)品名稱Anti-ERBB2 Antibody, Rabbit Polyclonal
 
經(jīng)驗證的應(yīng)用: WB

交叉反應(yīng)/
 
特異性human ERBB2
 
免疫原Recombinant human ERBB2 protein, fragment Tyr343~Thr652; UniprotKB: P04626
 
制備方法Produced in rabbits immunized with human ERBB2, and purified by antigen affinity chromatography.
 
來源Polyclonal Rabbit IgG
 
純化Immunogen affinity purified
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài)Liquid
 
運輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
別稱CD340, EGFR2, HER-2/neu, HER2, NEU, MLN 19, NGL, TKR1, p185, Epidermal Growth Factor Receptor 2, V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog
 
背景信息HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine  kinases. It has no ligand binding domain of its own and therefore cannot bind growth  factors. However, it does bind tightly to other ligand-bound EGF receptor family  members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving  mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification  and/or overexpression of HER2 have been reported in numerous cancers, including  breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast  cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.

全稱Receptor tyrosine-protein kinase erbB-2 (ERBB2)
 
說明書待上傳