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Anti-MKI67 Antibody, Rabbit Polyclonal

產(chǎn)品編號:PA00059HuA20
   
詢價

規(guī)格     50uL  100uL  200uL

說明書

產(chǎn)品名稱Anti-MKI67 Antibody, Rabbit Polyclonal

經(jīng)驗證的應用ICC
 
交叉反應/
 
特異性human MKI67
 
免疫原A synthetic peptide of  human MKI67; UniprotKB: P46013
 
制備方法Produced in rabbits immunized with human MKI67, and purified by antigen affinity chromatography.

來源Polyclonal Rabbit IgG
 
純化Immunogen affinity purified
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài)Liquid
 
運輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

圖片:



Figure1.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon  sections labelling MKI67 with purified PA00059HuA20 at 10ug/ml. Heat mediated antigen retrieval was performed using citrate buffer (pH 6.0).  Tissue was counterstained with Hematoxylin. Rabbit specific IHC polymer detection kit HRP/DAB secondary antibody was used at 1/4000 dilution. PBS instead of the primary antibody was used as the negative control.
 


別稱MKI67, KIA, Ki67P, Antigen Identified By Monoclonal Antibody Ki-67
 
背景信息The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. Ki67 is present during all active phases of the cell cycle (G1, S, G2 and M), but is absent in resting cells (G0). Cellular content of Ki-67 protein markedly increases during cell progression through S phase of the cell cycle. Therefore, the nuclear expression of Ki67 can be evaluated to assess tumor proliferation by immunohistochemistry. It has been demonstrated to be of prognostic value in breast cancer. In head and neck cancer, several studies have reported an association between high proliferative activity and poorer prognosis.
 
全稱Proliferation marker protein Ki-67 (MKI67)