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Anti-SERPINA1 Antibody, Rabbit Polyclonal

產(chǎn)品編號:PA00107HuA10
   
詢價

規(guī)格     50uL  100uL  200uL


說明書

產(chǎn)品名稱Anti-SERPINA1 Antibody, Rabbit Polyclonal

經(jīng)驗證的應用WB
 
交叉反應Predict reacts with: Human/Mouse/Rat
 
特異性human SERPINA1
 
免疫原Recombinant human SERPINA1 protein, fragment Glu25~Lys418; UniprotKB: P01009
 
制備方法Produced in rabbits immunized with human SERPINA1, and purified by antigen affinity chromatography.

來源Polyclonal Rabbit IgG
 
純化Immunogen affinity purified
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài)Liquid
 
運輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

圖片:






Figure 1. Application in WB
Western blot analysis of extracts of various cell lines, using SERPINA1 antibody (PA00107HuA10) at 1μg/mL. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Blocking buffer: 5% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5 s.
 
 










Figure 2. Application in WB
Western blot analysis of extracts of various cell lines, using SERPINA1 antibody (PA00107HuA10) at 1μg/mL. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Blocking buffer: 5% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1 s.






別稱SERPINA1, SPAAT, A1-AT, PI, Serpin Peptidase Inhibitor,Clade A(Alpha-1 Antiproteinase/AntiTrypsin)Member 1, Alpha-1 protease inhibitor, Short peptide from AAT, Serpin A1
 
背景信息Serpin A1/alpha 1-Antitrypsin. Serpin A1 is the archetypal member of the Serpin superfamily of the serine protease inhibitors (1). As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in the liver and secreted into the bloodstream with the major function to protect tissues against neutrophil elastase. A severe serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatitis, cirrhosis, and hepatocellular carcinoma (2). The deficiency is caused by point mutations in naturally occurring serpin A1 variants (over 70 are known). For example, the Z variant (Glu342 to Lys) forms intracellular inclusion bodies, is not secreted, and leads to a severe serpin A1 deficiency (3).
 
全稱Alpha-1-antitrypsin (SERPINA1)