Anti-CDH2 Antibody, Rabbit Polyclonal
產(chǎn)品編號(hào):PA00138HuA10
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產(chǎn)品名稱:Anti-CDH2 Antibody, Rabbit Polyclonal
經(jīng)驗(yàn)證的應(yīng)用:WB
交叉反應(yīng):/
特異性:human CDH2
免疫原:Recombinant human CDH2 protein, fragment Asp160~Phe497; UniprotKB: P19022
制備方法:Produced in rabbits immunized with human CDH2, and purified by antigen affinity chromatography.
來(lái)源:Polyclonal Rabbit IgG
純化:Immunogen affinity purified
緩沖液:Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶聯(lián)物:Unconjugated
狀態(tài):Liquid
運(yùn)輸方式:This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
儲(chǔ)存條件:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
圖片:
Figure 1. Application in WB
Western blot analysis of extracts of various cell lines and tissues, using CDH2 antibody (PA00138HuA10) at 1μg/mL. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Blocking buffer: 5% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 2 s.
別稱:CDw325, CD325, CDHN, CDH2, Cadherin 2 Type 1, N-Cadherin
背景信息:Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane glycoprotein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).
全稱:Cadherin-2 (CDH2)